Phase Solubility Studies of Poorly Soluble Drug Molecules by Using O-Phosphorylated Calixarenes as Drug-Solubilizing Agents Bayrakcı, M.; Ertul, Ş.; Yilmaz, M.; Journal of Chemical & Engineering Data 2012, 57, 233-239
- Journal: Journal of Chemical & Engineering Data
- Sample Quantity(ies): Molality
- Methodology: HPLC
- Phase(s): Liquid
- Substances:
- 5-(aminosulfonyl)-4-chloro-2-[(2-furanylmethyl)amino]benzoic acid C12H11ClN2O5S (ZZUFCTLCJUWOSV-UHFFFAOYSA-N) - Commercial source
- water H2O (XLYOFNOQVPJJNP-UHFFFAOYSA-N) - Commercial source
- tetrasodium 1,3,5,7(1,3)-tetrabenzenacyclooctaphane-1(2),3(2),5(2),7(2)-tetrayl tetrakis(hydrogen phosphate) C28H24Na4O16P4 (WMYJRIZEQHOLIR-UHFFFAOYSA-J) - Synthesized by the authors
Data
| m (mol kg-1) | m (mol kg-1) |
| 0.001 | 1.34 |
| 0.003 | 3.21 |
| 0.005 | 5.22 |
| 0.007 | 7.32 |
21713; 5-(aminosulfonyl)-4-chloro-2-[(2-furanylmethyl)amino]benzoic acid + water + tetrasodium 1,3,5,7(1,3)-tetrabenzenacyclooctaphane-1(2),3(2),5(2),7(2)-tetrayl tetrakis(hydrogen phosphate); 00004:04137:04139