Phase Solubility Studies of Poorly Soluble Drug Molecules by Using O-Phosphorylated Calixarenes as Drug-Solubilizing Agents Bayrakcı, M.; Ertul, Ş.; Yilmaz, M.; Journal of Chemical & Engineering Data 2012, 57, 233-239
- Journal: Journal of Chemical & Engineering Data
- Sample Quantity(ies): Molality
- Methodology: HPLC
- Phase(s): Liquid
- Substances:
- 5-(aminosulfonyl)-4-chloro-2-[(2-furanylmethyl)amino]benzoic acid C12H11ClN2O5S (ZZUFCTLCJUWOSV-UHFFFAOYSA-N) - Commercial source
- water H2O (XLYOFNOQVPJJNP-UHFFFAOYSA-N) - Commercial source
- octasodium 1(5),3(5),5(5),7(5),9(5),11(5),13(5),155-octa-tert-butyl-1,3,5,7,9,11,13,15(1,3)-octabenzenacyclohexadecaphane-1(2),3(2),5(2),7(2),9(2),11(2),13(2),15(2)-octayl octakis(hydrogen phosphate) C88H112Na8O32P8 (XAUBRQSUNUDDIE-UHFFFAOYSA-F) - Synthesized by the authors
Data
| m (mol kg-1) | m (mol kg-1) |
| 0.001 | 2.78 |
| 0.003 | 5.38 |
| 0.005 | 7.81 |
| 0.007 | 10.11 |
21716; 5-(aminosulfonyl)-4-chloro-2-[(2-furanylmethyl)amino]benzoic acid + water + octasodium 1(5),3(5),5(5),7(5),9(5),11(5),13(5),155-octa-tert-butyl-1,3,5,7,9,11,13,15(1,3)-octabenzenacyclohexadecaphane-1(2),3(2),5(2),7(2),9(2),11(2),13(2),15(2)-octayl octakis(hydrogen phosphate); 00004:04137:04142