Phase Solubility Studies of Poorly Soluble Drug Molecules by Using O-Phosphorylated Calixarenes as Drug-Solubilizing Agents Bayrakcı, M.; Ertul, Ş.; Yilmaz, M.; Journal of Chemical & Engineering Data 2012, 57, 233-239
- Journal: Journal of Chemical & Engineering Data
- Sample Quantity(ies): Molality
- Methodology: HPLC
- Phase(s): Liquid
- Substances:
- 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide C13H8Cl2N2O4 (RJMUSRYZPJIFPJ-UHFFFAOYSA-N) - Commercial source
- water H2O (XLYOFNOQVPJJNP-UHFFFAOYSA-N) - Commercial source
- disodium 1(5),3(5),5(5),7(5)-tetra-tert-butyl-3(2),7(2)-dihydroxy-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-1(2),5(2)-diyl bis(hydrogen phosphate) C44H56Na2O10P2 (SVJOBMCGJUFKEJ-UHFFFAOYSA-L) - Synthesized by the authors
Data
| m (mol kg-1) | m (mol kg-1) |
| 0.001 | 1.52 |
| 0.003 | 2.34 |
| 0.005 | 2.93 |
| 0.007 | 3.11 |
21724; 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide + water + disodium 1(5),3(5),5(5),7(5)-tetra-tert-butyl-3(2),7(2)-dihydroxy-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-1(2),5(2)-diyl bis(hydrogen phosphate); 00004:04140:04143